FERRUM HAUSMAN
| StockNo |
Product description |
Status |
| EB0280-101-09 |
FERRUM
HAUSMANN SYRUP VIAL 125 ML (1%) |
 |
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- COMPOSITION:
Ferric (III) hydroxide-polymaltosate complex 50 mg/5 ml syrup.
ACTION:
The peroral agents are more easily administered and more
physiological, because iron is directed to the bone marrow by a
normal way, stimulating erythropoiesis by enhanced production of red
blood cells. Absorption in the gastrointestinal tract takes place in
an ionized form (bivalent iron is more readily absorbed), but a
sufficient quantity of hydrochloride acid is needed for that
purpose. This is the reason why iron absorption is reduced during a
systematic administration of drugs neutralizing the hydrochloric
acid (sodium bicarbonate, calcium carbonate, magnesium oxide, etc.)
the reducing substances, such as ascorbic acid (vitamin C), improve
the absorption of iron, being the reason for administration of iron
drugs stabilized by vitamin C.
INDICATIONS:
Treatment of iron-deficient (hydrochronic) anemia of various
etiology - post-hemorrhage, gastroenterogenic, symptomatic
chloranemia, chlorosis, etc.
CONTRAINDICATIONS:
Febrility, acute infections, active pulmonary tuberculosis,
intestinal tuberculosis, ulcer disease of the stomach and duodenum,
acute and chronic catarrhal diseases of the stomach and intestines,
ulcerative colitis, hyperchloridria, hemochromatosis, hemolytic
anemia, thalassemia.
SIDE EFFECTS:
Gastrointestinal disturbances. Constipation is most often observed,
because iron binds to hydrogen sulphide in the intestines, which is
the physiological stimulant of intestinal peristalsis. Insoluble
sulphides are formed all over the intestinal mucosa isolating it
from the stimulations inducing peristalsis. Gastric complaints can
be reported with higher doses - nausea, vomiting, pain, loss of
appetite, sometimes diarrhea. The feces are dark during treatment
with the drug. |
DRUG INTERACTIONS:
The peroral iron agents disturb the absorption of various kinds of
tetracyclins, forming chelate complexes with them. Pancreas extracts
can inhibit iron absorption and diminish its action. Cholestyramide
can bind the iron in the gastrointestinal tract and hence impede its
absorption. The iron drugs can inhibit the absorption of
penicillamine. Vitamine E can reduce the therapeutic activity of the
drug.
DOSAGE AND ADMINISTRATION:
Orally, 1-2 h after meals to avoid gastric irritation and
inactivation of iron by some food components.
Adults - 1-2 teaspoonfuls, once daily. The duration of the treatment
depends on the condition of the patients and is determined by the
physician.
PRECAUTIONS:
During the treatment with peroral iron agents the intake of milk and
phytin-containing foods (nuts, wheat, oat flakes, etc.) should be
avoided, because iron absorption is reduced. Iron salts are
incompatible with tannins (they form ink-like compounds), so they
should not be taken in parallel with food containing tannins (red
wine, tea, coffee, etc.).
MEDICINAL FORM AND PACKAGE:
Syrup 1 % in vials of 125 ml.
STORAGE:
In a cool place (5-15° C).
EXPIRY:
5 (five) years.
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