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FERRUM HAUSMAN

 
StockNo Product description Status
EB0280-101-09 FERRUM HAUSMANN SYRUP VIAL 125 ML (1%)
 
COMPOSITION:
Ferric (III) hydroxide-polymaltosate complex 50 mg/5 ml syrup.

ACTION:
The peroral agents are more easily administered and more physiological, because iron is directed to the bone marrow by a normal way, stimulating erythropoiesis by enhanced production of red blood cells. Absorption in the gastrointestinal tract takes place in an ionized form (bivalent iron is more readily absorbed), but a sufficient quantity of hydrochloride acid is needed for that purpose. This is the reason why iron absorption is reduced during a systematic administration of drugs neutralizing the hydrochloric acid (sodium bicarbonate, calcium carbonate, magnesium oxide, etc.) the reducing substances, such as ascorbic acid (vitamin C), improve the absorption of iron, being the reason for administration of iron drugs stabilized by vitamin C.

INDICATIONS:
Treatment of iron-deficient (hydrochronic) anemia of various etiology - post-hemorrhage, gastroenterogenic, symptomatic chloranemia, chlorosis, etc.

CONTRAINDICATIONS:
Febrility, acute infections, active pulmonary tuberculosis, intestinal tuberculosis, ulcer disease of the stomach and duodenum, acute and chronic catarrhal diseases of the stomach and intestines, ulcerative colitis, hyperchloridria, hemochromatosis, hemolytic anemia, thalassemia.

SIDE EFFECTS:
Gastrointestinal disturbances. Constipation is most often observed, because iron binds to hydrogen sulphide in the intestines, which is the physiological stimulant of intestinal peristalsis. Insoluble sulphides are formed all over the intestinal mucosa isolating it from the stimulations inducing peristalsis. Gastric complaints can be reported with higher doses - nausea, vomiting, pain, loss of appetite, sometimes diarrhea. The feces are dark during treatment with the drug.

DRUG INTERACTIONS:
The peroral iron agents disturb the absorption of various kinds of tetracyclins, forming chelate complexes with them. Pancreas extracts can inhibit iron absorption and diminish its action. Cholestyramide can bind the iron in the gastrointestinal tract and hence impede its absorption. The iron drugs can inhibit the absorption of penicillamine. Vitamine E can reduce the therapeutic activity of the drug.

DOSAGE AND ADMINISTRATION:
Orally, 1-2 h after meals to avoid gastric irritation and inactivation of iron by some food components.
Adults - 1-2 teaspoonfuls, once daily. The duration of the treatment depends on the condition of the patients and is determined by the physician.

PRECAUTIONS:
During the treatment with peroral iron agents the intake of milk and phytin-containing foods (nuts, wheat, oat flakes, etc.) should be avoided, because iron absorption is reduced. Iron salts are incompatible with tannins (they form ink-like compounds), so they should not be taken in parallel with food containing tannins (red wine, tea, coffee, etc.).

MEDICINAL FORM AND PACKAGE:
Syrup 1 % in vials of 125 ml.

STORAGE:
In a cool place (5-15 C).

EXPIRY:
5 (five) years.

 

 

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EB0280 01/28/2001