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LYDOL
| StockNo |
Product description |
Status |
| EB0280-410-13 |
LYDOL
AMPOULE 2% 10 ML |
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- COMPOSITION:
Pethidine hydrochloride 2 % - 10 ml in one ampoule.
ACTION:
A synthetic narcotic of the piperidine group, analogous in
chemical structure to a part of themorphine molecule. Lydol is a
strong analgesic drug, its effect is shorterlived and weaker
than that of morphine. Its spasmolytic effect results from
direct myotropic and cholinolytic action which makes it very
suitable for pains of a spastic nature. Repeated application
leads to addiction and drug-dependence.
PHARMACOKINETICS:
Lydol is well absorbed after oral and parenteral administration.
Its analgesic effect is manifested about 15 min after oral
administration and 10 min after parenteral application. The
maximum effect comes about 2 h after its oral administration and
1 h after parenteral application.
INDICATIONS:
Pains with spasms in smooth-muscle organs (intestinal, biliary and
renal colics), angina pectoris, migraine, headache. Postoperative
pains and pains caused by cancer metastases, ischias, neuralgia,
neuritis, traumatic encephalopathy, epidemic encephalis, hiccup,
cough, as well as for potentiation of narcosis.
CONTRAINDICATIONS:
Dyspnoea (Cheyne-Stockers' respiration, etc) and increased
intracranial pressure. The preparation is not well tolerated by
patients with severe hepatic insufficiency. |
SIDE EFFECTS:
Dizziness, stupor, vomiting, xerostomia, collapse, headache,
perspiration, facial edema, urticaria. The preparation may provoke
spasms in the upper part of the gastrointestinal tract.
DRUG INTERACTIOONS:
Lydol increases the toxicity of anticholinergic substances of
glucocorticoids, the antidepressive drugs; the central inhibitory
action of barbiturates, phenothiazines and tricyclic depressants is
enhanced. The effect of Lydol is reduced by buprenorphine.
DOSAGE AND ADMINISTRATION:
Subcutaneously and intramuscularly - 1/2 to 1 ampoule, 1 to 3 times
daily. In acute and violent pains - an intravenous application is
possible (injected very slowly - for 2-3 min) in a dose of 0.25-1.00
ml of injection solution of lydol, diluted in 10 % solution of
glucose or saline.
MEDICINAL FORM AND PACKAGE:
Ampoules of 10 ml (2 %) in packs of 10 and 50.
STORAGE:
At moderate temperature (15-30 C).
EXPIRY:
5 (five) years. |
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