CHLOPHADON
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| StockNo |
Product description |
| EB0280-424-05 |
CHLOPHADON
50 TABL |
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- COMPOSITION:
Chlonidine 0.15 mg
Chlorthalidone 20 mg in one tablet
ACTION:
It is a combined drug of clofazoline with the diuretic saluretine.
It stimulates alpha-2-adrenergic receptors with a subsequent
inhibition of the vasomotor center and reduction of the arterial
pressure. It slows down the rate of cardiac contractions, does not
change renal blood flow, reduces peripheral vascular resistance. The
drug has a sedative effect. Saluretine has a long-lasting effect -
up to 72 h, inhibiting the reabsorption of sodium and chlorine ions
in the tubules in approximately equivalent ratios and dehydrating
the body.
The marked synergism between the two drugs is manifested in a better
antihypertensive effect obtained from the combination.
INDICATIONS:
All forms and stages of hypertonic disease, high diastolic
hypertension that failed to respond to the treatment with other
antihypertensive agents.
Grave organic cardiovascular damage with decompensation and
bradycardia, diabetes, gout, hypokalemia. |
SIDE EFFECTS:
Dryness in the mouth, sleepiness, lassitude and constipature, which
disappear within the first several weeks after the start of the
treatment.
DOSAGE AND ADMINISTRATION:
The treatment starts with 1/4 to 1/2 or 1 tablet, 1-3 times daily.
It can be prescribed to 6 tablets daily under clinical conditions
and constant control of electrolytes, blood sugar and uric acid.
Maintenance dose 1/2-1 tablet daily.
MEDICINAL FORM AND PACKAGE:
Packages of 50 tablets.
STORAGE:
At moderate temperature (15-30° C), in a place protected from
direct sunlight and moisture.
EXPIRY:
2 (two) years.
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