DIBAZOL
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| StockNo |
Product description |
| EB0280-444-03 |
DIBAZOL
TABL 20 MG X 40 |
| EB0280-444-16 |
DIBAZOL
TABL 5 MG X 100 |
| EB0280-444-17 |
DIBAZOL
AMPOULE 10 MG/2 ML (0.5%) |
-
- COMPOSITION:
Dibazol hydrochloride 10 mg/2 mg in one ampoule, 5 mg and 20 mg
in one tablet.
ACTION:
The preparation possesses a direct myotropic (papaverine-like)
action, with a vasodilating, spasmolytic and hypotensive effect. It
eliminates the deficit of ATP. It adapts the myocardium to hypoxia.
In small doses, it weakens the pressor systems and the local
vascular reactions. In higher doses it also has a spasmolytic action
on the gastrointestinal tract. It contributes to the elimination of
the foci of inhibition in CNS (resulting from a trauma or infection
damage, e.g. polimyelitis). It improves the conuction of the
impulses in the nervous synapses.
INDICATIONS:
The preparation is applied in cases of vascular spasms
(hypertension, hypertensive crises, cardiac insufficiency); spasms
of the smooth muscles of the internal organs (peptic ulcer of
stomach and duodenum; spasms of the pylorus and intestines, urinary
ducts, bronchi and uterus); diseases of the nervous system, mainly
for treatment of residual symptoms of poliomyelitis, paralysis of
the facial nerve, polyneuritis.
CONTRAINDICATIONS:
Diseases with increased muscular tone and convulsion syndromes.
SIDE EFFECTS:
Very high doses may cause increased perspiration, feeling of warmth,
slight headache, dizziness, nausea and decrease of BP. |
DOSAGE AND ADMINISTRATION:
Adults:
1. As a spasmolytic drug, dibazol is administered orally at doses of
0.02-0.05 g, 2-3 times daily (2 h before or 2 h after meals) or by
means of injection (subcutaneous and intramuscular) in doses of 2 to
4 ml of 0.5 % solution (0.01-0.02 g of active substance) once a day.
The treatment course lasts from 10 to 30 days.
2. In treatment of neurologic diseases the preparation is
administered in doses of 0.005-0.01 g every other day, every day or
2-3 times daily. An individual treatment scheme is necessary,
depending on the state and the therapeutic response of the patient.
3. In hypertensive crises the preparation is administered in doses
of 4 to 8 ml of 0.5 % solution (0.02-0.04) up to 3 times daily (the
solution must be warmed slightly before use in order to improve the
solubility).
Children:
For treatment of CNS diseases:
Age up to 1 year - 0.001
From 1 to 3 years - 0.002
From 3 to 8 years - 0.004
From 8 to 12 years - 0.005
Over 12 years - 0.005
MEDICINAL FORM AND PACKGE:
Ampoules of 10 mg/2 ml (0.5 %) in packs of 10, 50 and 100.
Tablets of 5 mg in packs of 100.
Tablets of 20 mg in packs of 40.
STORAGE:
At a moderate temperature (15-30° C).
EXPIRY:
2 (two) years.
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