SPASMALGON
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| StockNo |
Product description |
| EB0280-444-08 |
SPASMALGON
AMPOULE 2 ML |
| EB0280-444-22 |
SPASMALGON
AMPOULE 5 ML |
| EB0280-444-23 |
SPASMALGON
SOLUTION VIAL 10 ML |
-
- COMPOSITION:
Noramidopyrine methansulfonate sodium - 500 mg
Fenpiverin bromide - 2 mg
Pitofenom hydrochloride - 0.02 mg
in 1 ml injection solution
Noramidopyrine methansulfonate - 500 mg
Fenpiverin bromide - 50 mg
Pitofenom hydrochloride - 1 mg
in 10 ml solution
ACTION:
A combined drug with a potent spasmolytic and analgesic action. Its
spasmolytic effect is due to direct myotropic action and
M-cholinolytic action on the smooth muscles of the spastically
contracted organs. Its analgesic effect is determined by the central
and peripheral action of analgin included in the drug. Analgin, on
the one hand, reduces inflammation and inhibits the formation of
allogenic substances and, on the other, it stimulates the non-opiate
antinociceptive system by inhibiting the synthesis of
prostaglandins. Spasmalgon has a certain antipyretic and
antiphlogistic action. It suppresses the respiratory center and is
distinguished by its very quick and long-lasting effect. Injected
intramuscularly, the effect occurs after 20-30 min, intravenously -
after 2-3 min.
INDICATIONS:
Painful spasms of smooth muscles - renal colic, spasms of the
ureter, tenesmus of the urinary bladder, biliary colic, dyskinesia
of the biliary ducts, intestinal and gastric colic, spastic
dysmenorrhea, light and moderately severe paroxysms of bronchial
asthma.
CONTRAINDICATIONS:
Hypersensitivity to pyrazolone derivatives, glaucoma and hypertrophy
of prostate. |
SIDE EFFECTS:
The main side effects are due to hypersensitivity to analgin, the
most important being shock and changes in the blood count
(agranulocytosis and thrombocytopenia). Dryness of the mouth,
disturbed accommodation, urticarial rashes, skin and mucosa itching
can be observed, as well as disorders of the renal functions,
especially in predisposed patients.
PRECAUTIONS:
To be very cautiously administered to patients with low blood
pressure!
DOSAGE AND ADMINSTRATION:
Adult patients: parenterally in acute and severe colic pain -
intramuscularly or slowly intravenously, 5 ml injection solution at
an interval of 6-8 hours.
The drug is administered orally in light and moderately severe
spasms - 20-40 drops of the solution, 3 times daily.
MEDICINAL FORM AND PACKAGE:
Packages with 10 and 50 ampoules of 2 ml and 5 ml.
Solution in vials of 10 ml.
STORAGE:
At moderate temperature (15-30° C).
EXPIRY:
Ampoules - 3 (three) years.
Solution - 2 (two) years.
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